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Health Effects Assessment Summary (HEAST) for
Direct Black 38
CAS: 001937-37-7
Summary of HEAST Information on-Line
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Carcinogenicity |
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Carcinogenicity |
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Oral [Slope Factor]: (see comment) |
8.6E+0 (mg/kg/day)-1 |
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Oral [Unit Risk]: |
2.4E-4 (µg/L)-1 |
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Route: |
Oral: diet |
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Target Organ / Cancer: |
Liver / Tumors |
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Species |
Experiment Length |
EPA Group |
Rat |
93 days |
A |
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References |
1978 | NCI (National Cancer Institute). 1978. 13-week subchronic toxicity studies of Direct Blue 6, Direct Black 38, and Direct Brown 95 dyes. NCI Carcinogenesis Tech Rep Ser No. 108. P. 127. |
1987 | U.S. EPA. 1987. Health and environmental effects profile for Direct Black 38. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC. |
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Oral Slope Comment: |
Under review, number subject to change. |
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