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Health Effects Assessment Summary (HEAST) for
Diphenylhydrazine, 1,2-
CAS: 000122-66-7
Summary of HEAST Information on-Line
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Carcinogenicity |
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Carcinogenicity |
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Inhalation [Slope Factor]: (see comment) | 8.0E-1 (mg/kg/day)-1 |
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Route: |
Oral: diet |
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Target Organ / Cancer: |
Liver / Tumors |
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Species |
Experiment Length |
EPA Group |
Rat |
2 years |
IRIS |
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References |
1978 | NCI (National Cancer Institute). 1978. Bioassay of Hydrazobenzene for possible carcinogenicity. NCI Carcinogenesis Tech Rep Ser No. 92. DHEW Publ No. (NIH) 78-1342. |
1987 | U.S. EPA. 1987. Health effects assessment for 1,2-Diphenylhydrazine. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC. |
1988 | U.S. EPA. 1988. Health and environmental effects document for 1,2-Diphenylhydrazine. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC. |
1980 | U.S. EPA. 1980. Ambient Water Quality Criteria document for 1,2-Diphenylhydrazine. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Water Regulations and Standards, Washington, DC. |
1986 | .S. EPA. 1986. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group. |
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Inhalation Slope Comment: |
Based on route to route extrapolation. See Appendix A-II, Dose Conversions on HEAST. |
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