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Health Effects Assessment Summary (HEAST) for

Dinoseb

CAS: 000088-85-7


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)
1E-3 mg/kg/day

Uncertainty Factor: 1000

Route: Oral: diet

Target Organ / Critical Effect: Fetus / Decreased weight

Species Effect Level Dose Experiment Length
Rat LOAEL 1 mg/kg/day 29 weeks

References
1981 Dow Chemical Company. 1981. Confidential business information, unpublished study. MRID No. 00152675. Available from EPA. Write to FOI, EPA, Washington, DC 20460.
1984 U.S. EPA. 1984. Health and environmental effects profile for Dinoseb. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC
1986 U.S. EPA. 1986. RfD/RfC Work Group.

Subchronic [RfD] Comments: The chronic oral RfD was adopted as the subchronic oral [RfD].



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