Health Effects Assessment Summary (HEAST) for
Dinitrophenol, 2,4-
CAS: 000051-28-5
| Summary of HEAST Information on-Line | ||||||||
| Subchronic and Chronic Toxicity | ||||||||
|
| Subchronic [RfD]: (see comment) |
2E-3 mg/kg/day | |||
| Uncertainty Factor: | 1000 | |||
| Route: | Oral | |||
| Target Organ / Critical Effect: | Eye / Cataract | |||
| Species | Effect Level | Dose | ||
| Human | LOAEL | 2 mg/kg/day | ||
| References | ||||
| 1942 | Horner W.D. 1942. Dinitrophenol and its relation to formation of cataracts. Arch Ophthalmol. 27: 1097-1121. | |||
| 1984 | U.S. EPA. 1984. Health and environmental effects profile for Dinitrophenols (selected). Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington DC | |||
| 1991 | U.S. EPA. 1991. RfD/RfC Work Group. | |||
| Subchronic [RfD] Comments: | The chronic oral RfD was adopted as the subchronic oral [RfD]. | |||
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