Health Effects Assessment Summary (HEAST) for
Dimethylterephthalate
CAS: 000120-61-6
| Summary of HEAST Information on-Line | ||||||
| Subchronic and Chronic Toxicity | ||||||
|
| Subchronic [RfD]: (see comment) |
1E-1 mg/kg/day | |||
| Uncertainty Factor: | 1000 | |||
| Route: | Oral: diet | |||
| Target Organ / Critical Effect: | Kidney / Inflammation | |||
| Species | Effect Level | Dose | Experiment Length | |
| Rat | LOAEL | 125 mg/kg/day | 103 weeks | |
| References | ||||
| 1979 | NCI (National Cancer Institute). 1979. Bioassay of Dimethyl Terephthalate for possible carcinogenicity. DHEW/PUB/NIH 79-1376, NCI-CG-TR121. | |||
| 1984 | U.S. EPA. 1984. Health and environmental effects profile for Dimethyl and Methyl Terephthalate. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC | |||
| Subchronic [RfD] Comments: | The chronic oral RfD was adopted as the subchronic oral [RfD]. | |||
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