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Health Effects Assessment Summary (HEAST) for

Dimethylphenol, 3,4-

CAS: 000095-65-8


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 1E-2 mg/kg/day
Uncertainty Factor: 100

Route: Oral

Target Organ / Critical Effect: Whole body / Decreased weight
Organs, major / Lesions
Cardiovascular system / Altered blood pressure

Species Effect Level Dose Experiment Length
Rat NOEL 1.4 mg/kg/day 8 months

References
1979 Veldre I.A. and H.J. Janes. 1979. Toxicological studies of shale oils, some of their components and commercial products. Environ Health Perspect. 30: 141-146.
1987 U.S. EPA. 1987. Health effects assessment for Dimethylphenols. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC
1986 U.S. EPA. 1986. RfD/RfC Work Group.



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