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Health Effects Assessment Summary (HEAST) for
Dimethylaniline, n,n-
CAS: 000121-69-7
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Summary of HEAST Information on-Line
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| Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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| Subchronic [RfD]: |
2E-2 mg/kg/day |
| Uncertainty Factor: |
1000 |
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| Route: |
Oral: gavage |
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| Target Organ / Critical Effect: |
Spleen / Effects |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Mouse |
LOAEL |
22.32 mg/kg/day |
13 weeks |
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| References |
| 1984 | Abdo K., M. Wolfe and R. Hiles. 1984. Subchronic toxicity of n,n-Dimethylaniline to F-344 rats and B6C3F1 mice. Fed Proc. 43(3): 1698. |
| 1986 | U.S. EPA. 1986. Health and environmental effects profile for n,n-Dimethylaniline. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
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