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Health Effects Assessment Summary (HEAST) for
Diethylformamide
CAS: 000617-84-5
Summary of HEAST Information on-Line
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Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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Chronic [RfD]: |
1.1E-2 mg/kg/day |
Uncertainty Factor: |
100 |
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Subchronic [RfD]: |
1.1E-2 mg/kg/day |
Uncertainty Factor: |
100 |
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Route: |
Oral: gavage |
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Target Organ / Critical Effect: |
None observed |
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Species |
Effect Level |
Dose |
Experiment Length |
Rat |
NOEL |
0.546 mg/day, 5 days/ |
73 weeks |
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References |
1965 | Argus M.F., J.C. Arcos and C. Hoch-Ligeti. 1965. The carcinogenic activity of protein-denaturing agents: Hepatocarcinogenicity of Dioxane. J. Natl Cancer Inst. 35: 949-958. |
1986 | U.S. EPA. 1986. Health and environmental effects profile for Diethylformamide. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
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