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Health Effects Assessment Summary (HEAST) for

Diethylformamide

CAS: 000617-84-5


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:on-Line
Subchronic [RfD]:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Chronic [RfD]: 1.1E-2 mg/kg/day
Uncertainty Factor: 100

Subchronic [RfD]: 1.1E-2 mg/kg/day
Uncertainty Factor: 100

Route: Oral: gavage

Target Organ / Critical Effect: None observed

Species Effect Level Dose Experiment Length
Rat NOEL 0.546 mg/day, 5 days/ 73 weeks

References
1965 Argus M.F., J.C. Arcos and C. Hoch-Ligeti. 1965. The carcinogenic activity of protein-denaturing agents: Hepatocarcinogenicity of Dioxane. J. Natl Cancer Inst. 35: 949-958.
1986 U.S. EPA. 1986. Health and environmental effects profile for Diethylformamide. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC



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