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Health Effects Assessment Summary (HEAST) for

Dichlorophenol, 2,4-

CAS: 000120-83-2


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)
3E-3 mg/kg/day

Uncertainty Factor: 100

Route: Oral: drinking water

Target Organ / Critical Effect: Immune system / Altered immune function

Species Effect Level Dose Experiment Length
Rat NOEL 3 ppm 2 generations

References
1985 Exon J.H., and L.D. Koller. 1985. Toxicity of 2-Chlorophenol, 2,4-Dichlorophenol and 2,4,6-Trichlorophenol. In: Water chlorination: Chem, Environ Impact and Health Eff, Jolley et al., Ed. Vol. 5.
1987 U.S. EPA. 1987. Health and environmental effects document for Chlorinated Phenols. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC
1987 U.S. EPA. 1987. Health effects assessment for 2-Chlorophenol and 2,4-Dichlorophenol. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC
1986 U.S. EPA. 1986. RfD/RfC Work Group.

Subchronic [RfD] Comments: The chronic oral RfD was adopted as the subchronic oral [RfD].



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