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Health Effects Assessment Summary (HEAST) for
Dichlorophenol, 2,4-
CAS: 000120-83-2
Summary of HEAST Information on-Line
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Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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Subchronic [RfD]: (see comment) |
3E-3 mg/kg/day |
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Uncertainty Factor: |
100 |
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Route: |
Oral: drinking water |
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Target Organ / Critical Effect: |
Immune system / Altered immune function |
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Species |
Effect Level |
Dose |
Experiment Length |
Rat |
NOEL |
3 ppm |
2 generations |
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References |
1985 | Exon J.H., and L.D. Koller. 1985. Toxicity of 2-Chlorophenol, 2,4-Dichlorophenol and 2,4,6-Trichlorophenol. In: Water chlorination: Chem, Environ Impact and Health Eff, Jolley et al., Ed. Vol. 5. |
1987 | U.S. EPA. 1987. Health and environmental effects document for Chlorinated Phenols. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
1987 | U.S. EPA. 1987. Health effects assessment for 2-Chlorophenol and 2,4-Dichlorophenol. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC |
1986 | U.S. EPA. 1986. RfD/RfC Work Group. |
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Subchronic [RfD] Comments: |
The chronic oral RfD was adopted as the subchronic oral [RfD]. |
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