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Health Effects Assessment Summary (HEAST) for
Dichloroethylene, 1,2-trans-
CAS: 000156-60-5
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Summary of HEAST Information on-Line
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| Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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| Subchronic [RfD]: |
2E-1 mg/kg/day |
| Uncertainty Factor: |
100 |
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| Route: |
Oral: drinking water |
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| Target Organ / Critical Effect: |
Blood / Increased alkaline phosphatase |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Mouse |
NOAEL |
17 mg/kg/day |
90 days |
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| References |
| 1985 | Barnes D.W., W.M. Sanders, K.L. Shite Jr., et al. 1985. Toxicology of trans-1,2-Dichloroethylene in the mouse. Drug Chem Toxicol. 8: 373-392. |
| 1984 | U.S. EPA. 1984. Health effects assessment for 1,2-t-Dichloroethylene. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC |
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