Health Effects Assessment Summary (HEAST) for
Dichloro-2-Butene, 1,4-
CAS: 000764-41-0
| Summary of HEAST Information on-Line | ||||||||
| Carcinogenicity | ||||||||
|
| Inhalation [Slope Factor]: (see comment) | 9.3E+0 (mg/kg/day)-1 | |||
| Inhalation [Unit Risk]: | 2.6E-3 (µg/m3)-1 | |||
| Route: | Inhalation: intermittent | |||
| Target Organ / Cancer: | Nasal passages / Tumors | |||
| Species | Experiment Length | EPA Group | ||
| Rat | 90 days | B2 | ||
| References | ||||
| 1986 | EI Dupont De Nemours and Co. 1986. Long-term inhalation study with 1,4-Dichlorobutene-2 (DCB) in rats. Final report OTS 8(E) Fiche 0509754. | |||
| 1987 | U.S. EPA. 1987. Health and environmental effects document for Dichlorobutenes. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC. | |||
| General Comment: | Formerly listed under Dichlorobutenes. | |||
| Inhalation Slope Comment: | See Appendix A-II: Dose Conversions on HEAST. | |||
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