|
|
|
|
Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
|
| Subchronic [RfD]: |
1E+0 mg/kg/day |
| Uncertainty Factor: |
100 |
|
| Route: |
Oral: diet |
|
| Target Organ / Critical Effect: |
Whole body / Increased mortality |
|
| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
NOAEL |
125 mg/kg/day |
52 weeks |
|
| References |
| 1953 | Smith C.C. 1953. Toxicity of Butyl Stearate, Dibutyl Sebacate, Dibutyl Phthalate and Methoxyethyl Oleate. Arch Hyg Occup Med. 7: 310-318. |
| 1987 | U.S. EPA. 1987. Health effects assessment for selected Phthalic Acid Esters. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC |
| 1991 | U.S. EPA. 1991. Drinking water criteria document for Phthalic Acid Esters (PAE)s. Prepared by the Environmental Criteria and Assessment Office, Office of Health and Environmental Assessment, Cincinnati, OH, for the Office of Drinking Water, Washington, DC |
| 1990 | U.S. EPA. 1990. RfD/RfC Work Group. |
|
