|
|
|
|
Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
|
| Subchronic [RfD]: |
2E-1 mg/kg/day |
| Uncertainty Factor: |
100 |
|
| Route: |
Oral: gavage |
|
| Target Organ / Critical Effect: |
Liver / Lesions |
|
| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
NOEL |
21.4 mg/kg/day |
13 weeks |
|
| References |
| 1985 | NTP (National Toxicology Program). 1985. Toxicology and carcinogenesis studies of Chlorodibromomethane in F344/N rats and B6C3F1 mice (gavage studies). NTP TR282. NTIS PB86-166675. |
| 1985 | U.S. EPA. 1985. Health and environmental effects profile for Bromochloromethanes. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
| 1989 | U.S. EPA. 1989. Health and environmental effects document for Dibromochloromethane. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
| 1987 | U.S. EPA. 1987. RfD/RfC Work Group. |
|
