|
 
Health Effects Assessment Summary (HEAST) for
Dibromobenzene, 1,4-
CAS: 000106-37-6
|
Summary of HEAST Information on-Line
|
|
| Subchronic and Chronic Toxicity |
|
|
|
|
|
Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
|
| Subchronic [RfD]: |
1E-1 mg/kg/day |
| Uncertainty Factor: |
100 |
|
| Route: |
Oral: gavage |
|
| Target Organ / Critical Effect: |
Liver / Increased relative weight |
|
Liver / Altered enzyme activities |
|
| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
NOAEL |
10 mg/kg/day |
45 or 90 days |
|
| References |
| 1977 | Carlson G.P. and R.G. Tardiff. 1977. Effect of 1,4-Dibromobenzene and 1,2,4-Tribromobenzene on xenobiotic metabolism. Toxicol Appl Pharmacol. 42(1): 189-196. |
| 1984 | U.S. EPA. 1984. Health and environmental effects profile for Bromobenzenes. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
| 1986 | U.S. EPA. 1986. RfD/RfC Work Group. |
|
[ Risk Assessment Home ]
[ EPA Home |
OSWER Home | Superfund Home ]
[ Search EPA
| Search Superfund
| Whats New |
Contact Us ]
URL: http://risk.lsd.ornl.gov/epa/heast/heast_select.htm
This page was last updated on: March 1, 2000
Site maintained by: Office of Emergency and Remedial Response
Hofmann.Lee@epamail.epa.gov
|