|
|
|
|
Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
|
| Chronic [RfD]: |
9E-4 mg/kg/day |
| Uncertainty Factor: |
100 |
|
| Subchronic [RfD]: |
9E-4 mg/kg/day |
| Uncertainty Factor: |
100 |
|
| Route: |
Oral: diet |
|
| Target Organ / Critical Effect: |
Blood / Decreased cholinesterase activity |
|
| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
NOAEL |
0.09 mg/kg/day |
35-42 days |
|
| References |
| 1979 | Davies D.B. and B.J. Holub. 1979. Comparative susceptibility of male and female rats to dietary Diazinon toxicity. J Nutr. 109(6): XXVIII. |
| 1980 | Davies D.B. and B.J. Holub. 1980. Comparative subacute toxicity of dietary Diazinon in the male and female rat. Toxicol Appl Pharmacol. 54(3): 359-367. |
| 1980 | Davies D.B. and B.J. Holub. 1980. Toxicological evaluation of dietary Diazinon in the rat. Arch Environ Contam Toxicol. 9(6): 637-650. |
| 1984 | U.S. EPA. 1984. Health and environmental effects profile for Diazinon. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste, Washington, DC |
|
