Health Effects Assessment Summary (HEAST) for
Cyclopentadiene
CAS: 000542-92-7
| Summary of HEAST Information on-Line | ||||
| Alternative Methods | ||||
|
| Subchronic [RfC]: (see comment) |
3E+0 mg/cu m | |||
| Uncertainty Factor: | 100 | |||
| Route: | Inhalation: intermittent | |||
| Target Organ / Critical Effect: | Liver / Lesions | |||
| Kidney / Lesions | ||||
| Species | Effect Level | Dose | Experiment Length | |
| Rat | NOEL | 87.3 mg/kg/day | 194 days | |
| References | ||||
| 1987 | Dow. 1987. Unpublished data. Dow Chemical. U.SA, Midland, MI. | |||
| 1987 | U.S. EPA. 1987. Health and environmental effects document for Cyclopentadiene and Dicyclopentadiene. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC. | |||
| Subchronic [RfC] Comments: | 9E-1 mg/kg/day (see Appendix A-II, Dose Conversions on HEAST). | |||
| General Comments: | The subchronic inhalation [RfC] value was derived from methodology that is not current with the interim inhalation methodology used by the RfD/RfC work group. | |||
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