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Health Effects Assessment Summary (HEAST) for

Cyclohexylamine

CAS: 000108-91-8

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 3E-1 mg/kg/day
Uncertainty Factor: 100

Route: Oral: diet

Target Organ / Critical Effect: Whole body / Decreased weight gain
Testis / Decreased weight

Species Effect Level Dose Experiment Length
Rat NOAEL 30 mg/kg/day 90 days

References
1974 Gaunt I.F., M. Sharratt, P.G. Grasso, A.B. Lansdown and S.D. Gangolli. 1974. Short-term toxicity of Cyclohexylamine HCL in the rat. Food Cosmet Toxicol. 12: 609-624.
1987 U.S. EPA. 1987. Health and environmental effects document for Cyclohexylamine. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC


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