Health Effects Assessment Summary (HEAST) for
Crotonaldehyde
CAS: 000123-73-9
| Summary of HEAST Information on-Line | ||||||||
| Carcinogenicity | ||||||||
|
| Oral [Slope Factor]: (see comment) |
1.9E+0 (mg/kg/day)-1 | |||
| Oral [Unit Risk]: | 5.4E-5 (µg/L)-1 | |||
| Route: | Oral: drinking water | |||
| Target Organ / Cancer: | Liver / Tumor | |||
| Species | Experiment Length | EPA Group | ||
| Rat | 113 wks | IRIS | ||
| References | ||||
| 1986 | Chung, F.L., T. Tamaka, S.S. Hecht. 1986. Induction of liver tumors in F344 rats by Crotonaldehyde. Cancer Res. 46: 1285-1289. | |||
| 1989 | U.S. EPA. 1989. Health and environmental effects document for Crotonaldehyde. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC. | |||
| 1991 | U.S. EPA. 1991. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group. | |||
| Oral Slope Comment: | Under review, number subject to change. | |||
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