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Health Effects Assessment Summary (HEAST) for
Cresol, o- / (2-Methylphenol)
CAS: 000095-48-7
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Summary of HEAST Information on-Line
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| Subchronic and Chronic Toxicity |
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| Carcinogenicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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| Subchronic [RfD]: |
5E-1 mg/kg/day |
| Uncertainty Factor: |
100 |
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| Route: |
Oral: gavage |
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| Target Organ / Critical Effect: |
Whole body / Decreased weight gain |
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Nervous system / Neurotoxicity |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
NOAEL |
50 mg/kg/day |
90 days |
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| References |
| 1986 | U.S. EPA. 1986. o,m,p-Cresol. 90-day oral subchronic toxicity studies in rats. Office of Solid Waste, Washington, DC |
| 1987 | U.S. EPA. 1987. o,m,p-cresol. 90-day oral subchronic neurotoxicity study in rats. Office of Solid Waste, Washington, DC |
| 1987 | U.S. EPA. 1987. RfD/RfC Work Group. |
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