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Health Effects Assessment Summary (HEAST) for

Chromium III

CAS: 016065-83-1


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)
1.5E+0 mg/kg/day

Uncertainty Factor: 1000

Route: Oral: diet

Target Organ / Critical Effect: None observed

Species Effect Level Dose Experiment Length
Rat NOEL 5 % (Cr2O3) 840 days

References
1975 Ivankovic S. and R. Preussman. 1975. Absence of toxic and carcinogenic effects after administrations of high doses of Chromic Oxide pigment in subacute and long-term feeding experiments in rats. Food Cosmet Toxicol. 13: 347-351.
1984 U.S. EPA. 1984. Health effects assessment for Trivalent Chromium. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC
1986 U.S. EPA. 1986. RfD/RfC Work Group.

Subchronic [RfD] Comments: The chronic oral RfD was adopted as the subchronic oral [RfD].



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