|
|
|
|
Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
|
Subchronic [RfD]: (see comment) |
1.5E+0 mg/kg/day |
|
Uncertainty Factor: |
1000 |
|
Route: |
Oral: diet |
|
Target Organ / Critical Effect: |
None observed |
|
Species |
Effect Level |
Dose |
Experiment Length |
Rat |
NOEL |
5 % (Cr2O3) |
840 days |
|
References |
1975 | Ivankovic S. and R. Preussman. 1975. Absence of toxic and carcinogenic effects after administrations of high doses of Chromic Oxide pigment in subacute and long-term feeding experiments in rats. Food Cosmet Toxicol. 13: 347-351. |
1984 | U.S. EPA. 1984. Health effects assessment for Trivalent Chromium. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC |
1986 | U.S. EPA. 1986. RfD/RfC Work Group. |
|
Subchronic [RfD] Comments: |
The chronic oral RfD was adopted as the subchronic oral [RfD]. |
|