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Health Effects Assessment Summary (HEAST) for
Chlorpyrifos Methyl
CAS: 005598-13-0
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Summary of HEAST Information on-Line
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| Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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| Chronic [RfD]: |
1E-2 mg/kg/day |
| Uncertainty Factor: |
100 |
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| Subchronic [RfD]: |
1E-2 mg/kg/day |
| Uncertainty Factor: |
100 |
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| Route: |
Oral: diet |
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| Target Organ / Critical Effect: |
Reproduction / Decreased fertility |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
NOAEL |
1 mg/kg/day |
3 generations |
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| References |
| 1984 | U.S. EPA. 1984. Health and environmental effects profile for Chlorpyrifos and Chlorpyrifos-methyl. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
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| Chronic [RfD]: |
1E-2 mg/kg/day |
| Uncertainty Factor: |
100 |
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| Subchronic [RfD]: |
1E-2 mg/kg/day |
| Uncertainty Factor: |
100 |
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| Route: |
Oral: diet |
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| Target Organ / Critical Effect: |
Liver / Effects |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
NOAEL |
1 mg/kg/day |
2 years |
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| References |
| 1984 | U.S. EPA. 1984. Health and environmental effects profile for Chlorpyrifos and Chlorpyrifos-methyl. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
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