Health Effects Assessment Summary (HEAST) for
Chlorpyrifos
CAS: 002921-88-2
| Summary of HEAST Information on-Line | ||||||
| Subchronic and Chronic Toxicity | ||||||
|
| Subchronic [RfD]: (see comment) |
3E-3 mg/kg/day | |||
| Uncertainty Factor: | 10 | |||
| Route: | Oral: capsule | |||
| Target Organ / Critical Effect: | Blood / Decreased cholinesterase activity | |||
| Species | Effect Level | Dose | Experiment Length | |
| Human | NOEL | 0.03 mg/kg/day | 20 days or 9 days | |
| References | ||||
| 1972 | Dow Chemical Company. 1972. Confidential business information, unpublished study. Accession NO 112118. | |||
| 1984 | U.S. EPA. 1984. Health and environmental effects profile for Chlorpyrifos and Chloropyrifos-Methyl. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC | |||
| 1986 | U.S. EPA. 1986. RfD/RfC Work Group. | |||
| Subchronic [RfD] Comments: | The chronic oral RfD was adopted as the subchronic oral [RfD]. | |||
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