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Health Effects Assessment Summary (HEAST) for
Chlorotoluene, o-
CAS: 000095-49-8
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Summary of HEAST Information on-Line
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| Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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| Subchronic [RfD]: |
2E-1 mg/kg/day |
| Uncertainty Factor: |
100 |
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| Route: |
Oral: gavage |
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| Target Organ / Critical Effect: |
Whole body / Decreased weight gain |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
NOAEL |
20 mg/kg/day |
103 days |
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| References |
| 1974 | Gibson, W.R., F.O. Gossett, G.R. Koenig, F. Marroquin. 1974. The toxicity of daily oral doses of o-Chlorotoluene in the rat. Toxicology Division, Lilly Research Laboratories. Submitted to Test Rules Development Branch, Office of Toxic Substances, U.S. EPA, Washington, DC |
| 1989 | U.S. EPA. 1989. RfD/RfC Work Group. |
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