Health Effects Assessment Summary (HEAST) for
Chlorophenol, 2-
CAS: 000095-57-8
| Summary of HEAST Information on-Line | ||||||
| Subchronic and Chronic Toxicity | ||||||
|
| Subchronic [RfD]: (see comment) |
5E-2 mg/kg/day | |||
| Uncertainty Factor: | 100 | |||
| Route: | Oral: drinking water | |||
| Target Organ / Critical Effect: | Reproduction / Reproductive effects | |||
| Species | Effect Level | Dose | ||
| Rat | NOAEL | 50 ppm | ||
| References | ||||
| 1982 | Exon J.H., L.D. Koeller. 1982. Effects of transplacental exposure to Chlorinated Phenols. Environ Health Perspect. 46: 137-140. | |||
| 1987 | U.S. EPA. 1987. Health effects assessment for 2-Chlorophenol and 2,4-Dichlorophenol. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC | |||
| 1987 | U.S. EPA. 1987. Health and environmental effects document for Chlorinated Phenols. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC | |||
| 1990 | U.S. EPA. 1990. Health and environmental effects document for 2-Chlorophenol. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC | |||
| 1988 | U.S. EPA. 1988. RfD/RfC Work Group. | |||
| Subchronic [RfD] Comments: | Based on a reproductive study with exposure 10 weeks prior to and during mating, gestation and weaning. | |||
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