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Health Effects Assessment Summary (HEAST) for
Chloro-m-Cresol, p-
CAS: 000059-50-7
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Summary of HEAST Information on-Line
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| Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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| Subchronic [RfD]: |
2E+0 mg/kg/day |
| Uncertainty Factor: |
100 |
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| Route: |
Oral: gavage |
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| Target Organ / Critical Effect: |
Whole body / Decreased weight gain |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
NOAEL |
200 mg/kg/day |
28 days |
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| References |
| 1986 | Madsen C., P.H. Andersen, O. Meyer and G. Wurtzen. 1986. 4-Chloro-e-Methylphenol: Salmonella/mammalian-microsome mutagenicity test and subacute toxicity test in rats. Bull Environ Contam Toxicol. 37(5): 651-654. |
| 1988 | U.S. EPA. 1988. Health and environmental effects document for p-Chloro-m-Cresol. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
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