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Health Effects Assessment Summary (HEAST) for
Chloroacetic Acid
CAS: 000079-11-8
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Summary of HEAST Information on-Line
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| Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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| Chronic [RfD]: |
2E-3 mg/kg/day |
| Uncertainty Factor: |
10000 |
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| Subchronic [RfD]: |
2E-2 mg/kg/day |
| Uncertainty Factor: |
1000 |
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| Route: |
Oral: gavage |
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| Target Organ / Critical Effect: |
Heart / Myocarditis |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
LOAEL |
30 mg/kg |
13 weeks |
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| References |
| 1982 | IRDC (International Research and Development Corporation). 1982. Subchronic oral toxicity test with Monochloroacetic acid in rats. National Toxicology Program, Bethesda, MD p 1-101. |
| 1988 | U.S. EPA. 1988. Health and environmental effects document for Chloroacetic Acid. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
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