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Health Effects Assessment Summary (HEAST) for
Chloro-2-Methylaniline Hydrochloride, 4-
CAS: 003165-93-3
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Summary of HEAST Information on-Line
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| Carcinogenicity |
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Carcinogenicity |
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| Oral [Slope Factor]: |
4.6E-1 (mg/kg/day)-1 |
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| Oral [Unit Risk]: |
1.3E-5 (µg/L)-1 |
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| Route: |
Oral: diet |
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| Target Organ / Cancer: |
Cardiovascular system / Hemangioma |
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Cardiovascular system / Hemangiosarcoma |
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| Species |
Experiment Length |
EPA Group |
| Mouse |
18 months |
B2 |
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| References |
| 1978 | Weisburger E.K., A.B. Russfield, F. Homburger, et al. 1978. Testing of twenty-one environmental aromatic Amines or derivatives for long-term toxicity or carcinogenicity. J Environ Pathol Toxicol. 2: 325-356. |
| 1986 | U.S. EPA. 1986. Health and environmental effects profile for 4-Chloro-2-methylaniline and 4-Chloro-2-methylaniline Hydrochloride. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC. |
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