Health Effects Assessment Summary (HEAST) for
Chloral
CAS: 000075-87-6
| Summary of HEAST Information on-Line | ||||||
| Subchronic and Chronic Toxicity | ||||||
|
| Subchronic [RfD]: (see comment) |
2E-2 mg/kg/day | |||
| Uncertainty Factor: | 1000 | |||
| Route: | Oral: drinking water | |||
| Target Organ / Critical Effect: | Liver / Effects | |||
| Species | Effect Level | Dose | Experiment Length | |
| Mouse | LOAEL | 15.7 mg/kg/day | 90 days | |
| References | ||||
| 1982 | Sanders V.M., B.M. Kauffmann, K.L. White, Jr. 1982. Toxicology of Chloral Hydrate in the mouse. Environ Health Perspect. 44: 146-173. | |||
| 1988 | U.S. EPA. 1988. Health and environmental effects document for Chloral. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC | |||
| 1988 | U.S. EPA. 1988. RfD/RfC Work Group. | |||
| Subchronic [RfD] Comments: | The chronic oral RfD was adopted as the subchronic oral [RfD]. | |||
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