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Health Effects Assessment Summary (HEAST) for

Carbofuran

CAS: 001563-66-2

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)		 5E-3 mg/kg/day

Uncertainty Factor: 100

Route: Oral: diet

Target Organ / Critical Effect: Blood / Cholinesterase inhibition
Testis / Effects
Uterus / Effects

Species Effect Level Dose Experiment Length
Dog NOEL 0.5 mg/kg/day 1 year

References
1983 FMC Corporation. 1983. Confidential business information, unpublished study. Accession NO 250740-250755, MRID No. 00129507. Available from EPA. Write to FOI, EPA, Washington, DC 20460.
1984 U.S. EPA. 1984. Health and environmental effects profile for Carbofuran. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC
1987 U.S. EPA. 1987. RfD/RfC Work Group.
Subchronic [RfD] Comments: The chronic oral RfD was adopted as the subchronic oral [RfD].


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