|
|
|
|
Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
|
Subchronic [RfD]: (see comment) |
1E-1 mg/kg/day |
|
Uncertainty Factor: |
100 |
|
Route: |
Oral: diet |
|
Target Organ / Critical Effect: |
Kidney / Toxicity |
|
Liver / Toxicity |
|
Species |
Effect Level |
Dose |
Experiment Length |
Rat |
NOAEL |
9.6 mg/kg/day |
2 years |
|
References |
1961 | Carpenter C.P., C.W. Weil, P.E. Polin, et al. 1961. Mammalian toxicity of 1-Naphthyl-n-Methylcarbamate (Sevin insecticide). J Agric Food Chem. 9: 30-39. |
1984 | U.S. EPA. 1984. Health and environmental effects profile for Carbaryl. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
1985 | U.S. EPA. 1985. RfD/RfC Work Group. |
|
Subchronic [RfD] Comments: |
The chronic oral RfD was adopted as the subchronic oral [RfD]. |
|