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Health Effects Assessment Summary (HEAST) for
Caprolactam
CAS: 000105-60-2
Summary of HEAST Information on-Line
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Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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Subchronic [RfD]: |
5E-1 mg/kg/day |
Uncertainty Factor: |
100 |
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Route: |
Oral: diet |
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Target Organ / Critical Effect: |
Kidney / Effects |
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Species |
Effect Level |
Dose |
Experiment Length |
Rat |
NOAEL |
50 mg/kg/day |
90 days |
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References |
1984 | Powers W.J., J.C. Peckham, K.M. Siino and S.C. Gad. 1984. Effects of subchronic dietary Caprolactam on renal function. In: Proceedings of a symposium on an industry approach to chemical risk assessment: Caprolactam and related compounds as a case study. Industry Health Found. Arlington, VA. P 77-96. |
1988 | U.S. EPA. 1988. Health and environmental effects document for Caprolactam. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
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