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Health Effects Assessment Summary (HEAST) for

Butylate

CAS: 002008-41-5


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)
5E-2 mg/kg/day

Uncertainty Factor: 100

Route: Oral: capsule

Target Organ / Critical Effect: Liver / Increased relative weight

Species Effect Level Dose Experiment Length
Dog NOEL 5 mg/kg/day 12 months

References
1987 Stauffer Chemical Company. 1987. Confidential business information, unpublished study. MRID No. 40289101. Available from EPA. Write to FOI, EPA, Washington, DC 20460.
1984 U.S. EPA. 1984. Health and environmental effects profile for Butylate. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC
1989 U.S. EPA. 1989. RfD/RfC Work Group.

Subchronic [RfD] Comments: The chronic oral RfD was adopted as the subchronic oral [RfD].



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