EPA Home PageSuperfund Risk Assessment Home Page


Health Effects Assessment Summary (HEAST) for

Butanol, 1-

CAS: 000071-36-3

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 1E+0 mg/kg/day
Uncertainty Factor: 100

Route: Oral: gavage

Target Organ / Critical Effect: Central nervous system / Hypoactivity
Central nervous system / Ataxia

Species Effect Level Dose Experiment Length
Rat NOAEL 125 mg/kg/day 13 weeks

References
1986 U.S. EPA. 1986. Butanol: Rat oral subchronic toxicity study. Office of Solid Waste and Emergency Response, Washington, DC
1989 U.S. EPA. 1989. Health and environmental effects document for 1-Butanol. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC
1986 U.S. EPA. 1986. RfD/RfC Work Group.


[ Risk Assessment Home ]
[ EPA Home | OSWER Home | Superfund Home ]
[ Search EPA | Search Superfund | Whats New | Contact Us ]
Horizontal Rule
URL: http://risk.lsd.ornl.gov/epa/heast/heast_select.htm
This page was last updated on: March 1, 2000
Site maintained by: Office of Emergency and Remedial Response
Hofmann.Lee@epamail.epa.gov
Horizontal Rule