Health Effects Assessment Summary (HEAST) for
Butadiene, 1,3-
CAS: 000106-99-0
| Summary of HEAST Information on-Line | ||||||||
| Carcinogenicity | ||||||||
|
| Inhalation [Slope Factor]: (see comment) | 1.8E+0 (mg/kg/day)-1 | |||
| Route: | Inhalation: intermittent | |||
| Target Organ / Cancer: | Multiple sites / Tumors | |||
| Species | EPA Group | |||
| Mouse | IRIS | |||
| References | ||||
| 1984 | NTP (National Toxicology Program). 1984. Toxicology and carcinogenesis studies of 1,3-Butadiene (CAS 106-99-0) in B6C3F1 mice (inhalation studies). | |||
| 1985 | U.S. EPA. 1985. Mutagenicity and carcinogenicity assessment of 1,3-Butadiene. Office of Health and Environmental Assessment, Washington, DC. EPA 600/8-85-004f. NTIS-PB86-12507. | |||
| 1989 | U.S. EPA. 1989. Health and environmental effects document for 1,3-Butadiene. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC. | |||
| 1987 | U.S. EPA. 1987. Carcinogen Risk Assessment Verification (CRAVE) Work Group. | |||
| Inhalation Slope Comment: | See Appendix A-II, Dose Conversions on HEAST. | |||
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