Health Effects Assessment Summary (HEAST) for
Bromophos
CAS: 002104-96-3
| Summary of HEAST Information on-Line | ||||||
| Subchronic and Chronic Toxicity | ||||||
|
| Chronic [RfD]: (see comment) |
5E-3 mg/kg/day | |||
| Uncertainty Factor: | 1000 | |||
| Subchronic [RfD]: (see comment) |
5E-2 mg/kg/day | |||
| Uncertainty Factor: | 100 | |||
| Route: | Oral: diet | |||
| Target Organ / Critical Effect: | Blood / Decreased cholinesterase activity | |||
| Liver / Decreased cholinesterase activity | ||||
| Species | Effect Level | Dose | Experiment Length | |
| Rat | NOAEL | 5 mg/kg/day | 3 generations | |
| References | ||||
| 1967 | Leuschner F., A. Leuschner and E. Poppe. 1967. Chronischer reproduktionsversuch uber 3 generationen an Wistar-ratten bei fortdauerner verabreichung von Bromophos. Report CH Boehringer Sohn. (unpublished). | |||
| 1986 | U.S. EPA. 1986. Health and environmental effects profile for Bromophos. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC | |||
| Subchronic [RfD] Comments: | Based on a reproduction study. | |||
| Chronic [RfD] Comments: | Based on a reproduction study. | |||
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