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Health Effects Assessment Summary (HEAST) for

Bisphenol A

CAS: 000080-05-7


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 6E-1 mg/kg/day
Uncertainty Factor: 100

Route: Oral

Target Organ / Critical Effect: Whole body / Decreased weight

Species Effect Level Dose Experiment Length
Rat NOAEL 750 ppm 13 weeks

References
1982 NTP (National Toxicology Program). 1982. Carcinogenesis bioassay of Bisphenol a in F344 rats and B6C3F1 mice (feed study). NTP Tech Rep Ser. No. 80-35 NTIS PB 84-1555308 p. 192.
1988 U.S. EPA. 1988. Health and environmental effects document for Bisphenol A. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC



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