Health Effects Assessment Summary (HEAST) for
Bis(Chloromethyl) Ether
CAS: 000542-88-1
| Summary of HEAST Information on-Line | ||||||||||||
| Carcinogenicity | ||||||||||||
|
| Inhalation [Slope Factor]: (see comment) | 2.2E+2 (mg/kg/day)-1 | |||
| Route: | Inhalation: intermittent | |||
| Target Organ / Cancer: | Respiratory system / Tumors | |||
| Species | Experiment Length | EPA Group | ||
| Rat | 10-100 days | IRIS | ||
| References | ||||
| 1975 | Kuschner, M., S. Laskin, R.T. Drew, et al. 1975. Inhalation carcinogenicity of alpha halo Ethers: III. Lifetime and limited period inhalation studies with Bis(chloromethyl) Ether at 0.1 ppm. Arch Environ Health. 30(2): 73-77. | |||
| 1988 | U.S. EPA. 1988. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group. | |||
| Inhalation Slope Comment: | See Appendix A-II, Dose Conversions on HEAST. | |||
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