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Health Effects Assessment Summary (HEAST) for

Bis(2-Chloroisopropyl)Ether

CAS: 039638-32-9

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 4E-2 mg/kg/day
Uncertainty Factor: 1000

Route: Oral: diet

Target Organ / Critical Effect: Erythrocytes / Decreased hemoglobin

Species Effect Level Dose Experiment Length
Mouse NOAEL 35.8 mg/kg/day 2 years

References
1979 Mitsumori K., T. Usui, K. Takahashi, and Y. Shirasu. 1979. Twenty-four month chronic toxicity studies of Dichlorodiisopropyl Ether in mice. Nippon Noyaku Gakkaishi. 4(3): 323-335.
1989 U.S. EPA. 1989. RfD/RfC Work Group.


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