Health Effects Assessment Summary (HEAST) for
Bis(2-Chloroethyl) Ether
CAS: 000111-44-4
| Summary of HEAST Information on-Line | ||||||||||||
| Carcinogenicity | ||||||||||||
|
| Inhalation [Slope Factor]: (see comment) | 1.1E+0 (mg/kg/day)-1 | |||
| Route: | Oral | |||
| Target Organ / Cancer: | Liver / Tumors | |||
| Species | Experiment Length | EPA Group | ||
| Mouse | 560 days | IRIS | ||
| References | ||||
| 1969 | Innes, J.R.M., B.M. Ulland, M.G. Valerio et al. 1969. Bioassay of pesticides and industrial chemicals for tumorigenicity in mice: a preliminary note. J Natl Cancer Inst 42: 1101-1114. | |||
| 1987 | U.S. EPA. 1987. Health effects assessment for bis(2-Chloroethyl) Ether. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC. | |||
| 1980 | U.S. EPA. 1980. Ambient Water Quality Criteria document for chloroalkyl Ethers. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Water Regulations and Standards, Washington, DC. | |||
| 1986 | U.S. EPA. 1986. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group. | |||
| Inhalation Slope Comment: | Based on route to route extrapolation. See Appendix A-II, Dose Conversions on HEAST. | |||
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