Health Effects Assessment Summary (HEAST) for
Biphenyl, 1,1'
CAS: 000092-52-4
| Summary of HEAST Information on-Line | ||||||||
| Subchronic and Chronic Toxicity | ||||||||
|
| Subchronic [RfD]: (see comment) |
5E-2 mg/kg/day | |||
| Uncertainty Factor: | 1000 | |||
| Route: | Oral: diet | |||
| Target Organ / Critical Effect: | Kidney / Damage | |||
| Species | Effect Level | Dose | Experiment Length | |
| Rat | NOAEL | 50 mg/kg/day | 700 days | |
| References | ||||
| 1960 | Ambrose A.M., A.N. Booth, F. de Eds and A.J. Cos Jr. 1960. A toxicological study of Biphenyl, a citrus fungistat. Food Res. 25: 328-336. | |||
| 1984 | U.S. EPA. 1984. Health and environmental effects profile for 1,1'-Biphenyl. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC | |||
| 1985 | U.S. EPA. 1985. RfD/RfC Work Group. | |||
| Subchronic [RfD] Comments: | The chronic oral RfD was adopted as the subchronic oral [RfD]. | |||
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