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Health Effects Assessment Summary (HEAST) for

Benzyl Alcohol

CAS: 000100-51-6


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:on-Line
Subchronic [RfD]:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Chronic [RfD]: 3E-1 mg/kg/day
Uncertainty Factor: 1000

Route: Oral: gavage

Target Organ / Critical Effect: Forestomach / Epithelial hyperplasia

Species Effect Level Dose Experiment Length
Rat LOAEL 286 mg/kg/day 103 weeks

References
1988 NTP (National Toxicology Program). 1988. Toxicology and carcinogenesis studies of Benzyl Alcohol (CAS No. 100-51-6) in F344/N rats and B6C3F1 mice (gavage studies). NTP technical report, NTP TR 343. P 1-161.





Subchronic [RfD]: 1E+0 mg/kg/day
Uncertainty Factor: 100

Route: Oral: gavage

Target Organ / Critical Effect: Whole body / Decreased weight

Species Effect Level Dose Experiment Length
Rat NOAEL 143 mg/kg/day 13 weeks

References
1988 NTP (National Toxicology Program). 1988. Toxicology and carcinogenesis studies of Benzyl Alcohol (CAS No. 100-51-6) in F344/N rats and B6C3F1 mice (gavage studies). NTP technical report, NTP TR 343. P 1-161.
1989 U.S. EPA. 1989. Health and environmental effects document for Benzyl Alcohol. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC



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