|
|
|
|
Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
|
Subchronic [RfD]: (see comment) |
4E+0 mg/kg/day |
|
Uncertainty Factor: |
1 |
|
Route: |
Oral: diet |
|
Target Organ / Critical Effect: |
None observed |
|
Species |
Effect Level |
Dose |
|
Human |
NOAEL |
312 mg/day |
|
|
References |
1973 | FDA (Food and Drug Administration). 1973. Evaluation of the health aspects of Benzoic Acid and Sodium Benzoate as food ingredients. DHEW, Washington, DC Report No. SCOGS-7 NTIS PB-223 837/6. P.17. |
1987 | U.S. EPA. 1987. Health and environmental effects document for Benzoic Acid. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
1987 | U.S. EPA. 1987. RfD/RfC Work Group. |
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Subchronic [RfD] Comments: |
The human daily per capita intake was used as the critical dose level. The chronic oral RfD was adopted as the subchronic oral [RfD]. |
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