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Health Effects Assessment Summary (HEAST) for

Benzoic Acid

CAS: 000065-85-0


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)
4E+0 mg/kg/day

Uncertainty Factor: 1

Route: Oral: diet

Target Organ / Critical Effect: None observed

Species Effect Level Dose
Human NOAEL 312 mg/day

References
1973 FDA (Food and Drug Administration). 1973. Evaluation of the health aspects of Benzoic Acid and Sodium Benzoate as food ingredients. DHEW, Washington, DC Report No. SCOGS-7 NTIS PB-223 837/6. P.17.
1987 U.S. EPA. 1987. Health and environmental effects document for Benzoic Acid. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC
1987 U.S. EPA. 1987. RfD/RfC Work Group.

Subchronic [RfD] Comments: The human daily per capita intake was used as the critical dose level. The chronic oral RfD was adopted as the subchronic oral [RfD].



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