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Health Effects Assessment Summary (HEAST) for

Benzene

CAS: 000071-43-2


Summary of HEAST Information on-Line

Carcinogenicity
Oral [Slope Factor]:IRIS
Inhalation [Slope Factor]:on-Line
Oral [Unit Risk]:IRIS
Inhalation [Unit Risk]:IRIS
EPA Group:IRIS
Notes/Comments:on-Line






Carcinogenicity

Inhalation [Slope Factor]:
(see comment)
2.9E-2 (mg/kg/day)-1


Route: Inhalation: occupational

Target Organ / Cancer: Blood / Leukemia

Species EPA Group
Human IRIS

References
1983 Wong O., R.W. Morgan and M.D. Whorton. 1983. Comments on the NIOSH study of leukemia in Benzene workers. Technical report submitted to Gulf Canada, LTD, by Environmental Health Associates, August 31. Cited in U.S. EPA, 1985.
1978 Ott M.G., J.C. Townsend, W.A. Fishbeck and R.A. Langner. 1978. Mortality among workers occupationally exposed to Benzene. Arch Environ Health 33: 3-10.
1981 Rinsky R.A., R.J. Young and A.B. Smith. 1981. Leukemia in Benzene workers. Am J Ind Med 2: 217-245.
1987 U.S. EPA. 1987. Memorandum from J. Orme Heb, CSD/ODW to C. Vogt, June, 1987. Criteria and Standards Division, ODW.
1985 U.S. EPA. 1985. Interim quantitative cancer unit risk estimates due to inhalation of Benzene. Office of Health and Environmental Assessment, Carcinogen Assessment Group, Washington, DC. Office of Air Quality Planning and Standards, Washington, DC.
1987 U.S. EPA. 1987. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group.

Inhalation Slope Comment: See Appendix A-II, Dose Conversions on HEAST.



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