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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
|
Subchronic [RfD]: (see comment) |
3E-1 mg/kg/day |
|
Uncertainty Factor: |
100 |
|
Route: |
Oral: diet |
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Target Organ / Critical Effect: |
Erythrocytes / Decreased count |
|
Species |
Effect Level |
Dose |
Experiment Length |
Dog |
NOAEL |
25 mg/kg/day |
1 year |
|
References |
1972 | Eli Lilly and Co. 1972. Confidential business information, unpublished study. MRID No. 00037678. Available from EPA. Write to FOI, EPA, Washington, DC 20460. |
1984 | U.S. EPA. 1984. Health and environmental effects profile for Benefin. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
1985 | U.S. EPA. 1985. RfD/RfC Work Group. |
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Subchronic [RfD] Comments: |
The chronic oral RfD was adopted as the subchronic oral [RfD]. |
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