|
|
|
|
Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
|
Chronic [RfD]: (see comment) |
4E-4 mg/kg/day |
|
Uncertainty Factor: |
1000 |
|
Subchronic [RfD]: (see comment) |
4E-4 mg/kg/day |
|
Uncertainty Factor: |
1000 |
|
Route: |
Oral: drinking water |
|
Target Organ / Critical Effect: |
Whole body / Increased mortality |
|
Blood / Altered chemistries |
|
Species |
Effect Level |
Dose |
Experiment Length |
Rat |
LOAEL |
0.44 mg/kg/day |
Lifetime |
|
References |
1970 | Schroeder H.A., M. Mitchener and A.P. Nason. 1970. Zirconium, Niobium, Antimony and Lead in rats: Life-time studies. J Nutr. 100: 59-69. |
1987 | U.S. EPA. 1987. Health effects assessment for Antimony and compounds. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC |
1985 | U.S. EPA. 1985. Health and environmental effects profile for Antimony Oxides. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
|
Subchronic [RfD] Comments: |
Calculated by analogy to Antimony by correcting for differences in molecular weight. |
Chronic [RfD] Comments: |
Calculated by analogy to Antimony by correcting for differences in molecular weight. |
|