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Health Effects Assessment Summary (HEAST) for
Aniline
CAS: 000062-53-3
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Summary of HEAST Information on-Line
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| Subchronic and Chronic Toxicity |
|
| Carcinogenicity |
| Oral [Slope Factor]: | IRIS |
| Oral [Unit Risk]: | IRIS |
| EPA Group: | IRIS |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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| Subchronic [RfC]: |
1E-2 mg/cu m |
| Uncertainty Factor: |
300 |
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| Route: |
Inhalation: intermittent |
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| Target Organ / Critical Effect: |
Spleen / Pathology |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Mouse, Rat, Guinea pig |
NOAEL |
19 mg/cu m |
20-26 weeks |
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| References |
| 1956 | Oberst F.W., E. Hackley, C. Comstock. 1956. Chronic toxicity of Aniline vapor (5ppm) by inhalation. Arch Ind Health. 13: 379-384. |
| 1985 | U.S. EPA. 1985. Health and environmental effects profile for Aniline. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
| 1990 | U.S. EPA. 1990. RfD/RfC Work Group. |
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