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Health Effects Assessment Summary (HEAST) for

Acetophenone

CAS: 000098-86-2

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 1E+0 mg/kg/day
Uncertainty Factor: 300

Route: Oral: diet

Target Organ / Critical Effect: None observed

Species Effect Level Dose Experiment Length
Rat NOAEL 10,000 ppm 17 weeks

References
1967 Hagan, E.C., W.H. Hansen, D.G. Fitzhugh, et al. 1967. Food flavorings and compounds of related structure. II. Subacute and chronic toxicity. Food Cosmet Toxicol. 5(2): 141-157.
1987 U.S. EPA. 1987. RfD/RfC Work Group.


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