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Health Effects Assessment Summary (HEAST) for

Acephate

CAS: 030560-19-1

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Carcinogenicity
Oral [Slope Factor]:IRIS
Oral [Unit Risk]:IRIS
EPA Group:IRIS





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 4E-3 mg/kg/day
Uncertainty Factor: 30

Route: Oral: diet

Target Organ / Critical Effect: Brain / Decreased cholinesterase activity

Species Effect Level Dose Experiment Length
Rat LOAEL 2 ppm 13 weeks

References
1987 Chevron Chemical Company. 1987. Confidential business information unpublished data. MRID No. 40504819
1984 U.S. EPA. 1984. Health and environmental effects profile for Acephate. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC
1989 U.S. EPA. 1989. RfD/RfC Work Group.


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