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Health Effects Assessment Summary (HEAST) for

Methyl-4-Chlorophenoxyacetic Acid, 2-

CAS: 000094-74-6


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)
5E-4 mg/kg/day

Uncertainty Factor: 300

Route: Oral: diet

Target Organ / Critical Effect: Kidney / Effects
Liver / Effects

Species Effect Level Dose Experiment Length
Dog NOEL 0.15 mg/kg/day 52 weeks

References
1986 Industry Task Force on MCPA Research Data. 1986. Confidential business information, unpublished study. MRID No. 00164352. Available from EPA. Write to FOI, EPA, Washington, DC 20460.
1984 U.S. EPA. 1984. Health and environmental effects profile for MCPA and MCPB. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste, Washington, DC
1988 U.S. EPA. 1988. RfD/RfC Work Group.

Subchronic [RfD] Comments: The chronic oral RfD was adopted as the subchronic oral [RfD].



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